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Building Patient Support Programs That Improve Retention, Engagement, and Compliance

Life Sciences & Healthcare

Last Updated: November 11, 2025

“Patient-centric care” has become the buzzword of the moment in healthcare and life sciences. But let’s be real—that’s just the starting line. The real test is whether your organization is actually delivering it.

Right now, too many Patient Support Programs (PSPs) are built on shaky foundations: fragmented systems, manual processes, and data trapped in silos. No wonder these programs fail to scale, frustrate patients, and drain resources.

In fact, the numbers are pretty telling. A report by BioPharma Dive found that pharmaceutical manufacturers spend over $5 billion a year on patient support programs, yet only about 3% of eligible patients ever actually enroll and use them. That’s a massive investment for a minimal return.

Why the huge gap? It’s not a single flaw; it’s a series of deeply rooted pain points that create a workflow built on friction.

Why Current PSPs Fall Short

Manual processes. Intake, consent, and insurance verification are often handled through paper forms or spreadsheets. These processes are slow, error-prone, and a massive administrative burden that pulls valuable team members away from direct patient interaction. When a patient is already dealing with a serious medical condition, the last thing they need is a dozen forms and a long phone call where they have to repeat the same information over and over.

Disconnected systems. Many PSPs rely on legacy platforms that don’t talk to each other. According to CapMinds, 72% of hospitals struggle with patient data gaps. The result is a fragmented view of the patient. One team can’t see what another has done, leading to duplicated effort, repeated questions, and a frustrating, disjointed experience for the patient.

Scaling challenges. A program built for one therapy often can’t scale across a broader portfolio without costly, time-consuming rebuilds. This is a huge roadblock for organizations looking to expand their offerings or launch new products. The underlying technology isn’t flexible enough to adapt, locking you into a one-off model that can’t grow with your business.

Compliance complexity. Regulations like HIPAA, GDPR, and GxP create layers of requirements that can slow down innovation. If these rules aren’t designed into the system from the start, a new feature can take months to deploy. You’re constantly playing catch-up, trying to patch security and compliance onto a system that wasn’t built for it.

Limited data visibility. Without real-time insights, it’s impossible to course-correct patient journeys quickly. You can’t tell if a patient is falling off their treatment plan or facing a new barrier until it’s too late. By the time you spot a drop-off, the opportunity to intervene has already passed. Trying to build a great patient experience with that kind of setup is like trying to build a skyscraper with a pile of bricks. It’s just not going to work.

What Good Looks Like

When PSPs are built on solid, patient-first foundations, the results go far beyond numbers. They translate into trust, seamless experiences, and better health outcomes.

  • A pharma company in Latin America modernized its PSP and achieved a 40% increase in adherence and a 45% boost in patient satisfaction.
  • An IQVIA study showed patients in a comprehensive PSP were 69% likely to stay on medication after one year, compared to 55% in a control group—a direct impact on outcomes and costs.

The lesson is clear: when PSPs are frictionless, patients engage and stay the course.

Five Priorities for Next-Gen PSPs

You can’t just layer new tech on top of old problems. Transformation starts at the foundation. The best programs share five critical traits:

  1. Visibility First
    A single view of the patient journey is essential. If systems are fragmented, integration—not another siloed tool—must come first.
  2. Automate the Routine
    Insurance checks, consent management, reminders—these should run in the background. Automation frees staff for what matters most: empathetic, human interaction.
  3. Design for Scale
    Programs should flex as new therapies and products are added, without costly rebuilds.
  4. Build in Compliance
    When security and privacy are embedded from the start, compliance becomes a driver of trust instead of a drag on speed.
  5. Make Analytics Actionable
    Dashboards shouldn’t just inform—they should trigger real-time interventions when patients are at risk of falling off therapy.

How Hexaware Helps

At Hexaware, we don’t start with systems or departments—we start with the patient journey. From prescription to adherence, we map every touchpoint and redesign processes around what patients and care teams actually need.

Our framework follows three simple phases:

  • Assess & Strategize – We capture the full landscape, identify pain points, and build a scalable roadmap aligned with both business goals and patient needs.
  • Build the Foundation – Leveraging modern platforms like Salesforce Health Cloud and Service Cloud, we create integrated, automated, compliant systems that can grow with your portfolio.
  • Deliver & Optimize – Through rigorous validation and continuous improvement, we ensure PSPs don’t just launch—they evolve.

This patient-first model shifts PSPs from being cost centers to becoming strategic enablers of engagement, loyalty, and outcomes.

Proof in Action

We’ve seen measurable success across global pharma and specialty care providers. The below success stories aren’t just operational wins—they’re real patient outcomes, amplified by technology that makes support seamless:

  • Retention at Scale
    A global pharma firm cut onboarding time dramatically by automating intake and insurance checks. Result: 92% improvement in patient retention during early therapy stages.
  • Engagement That Lasts
    A specialty care provider redesigned communication with digital reminders, ambassador programs, and real-time dashboards. Patient engagement jumped 75%, giving providers early signals when patients needed extra support.
  • Adherence That Delivers Outcomes
    In a chronic disease program, predictive analytics flagged at-risk patients before they dropped out. Medication adherence improved by 80%, boosting therapeutic outcomes and patient satisfaction.

The Future of Patient Support

The next wave of PSPs won’t just manage patients; they’ll anticipate needs. AI and machine learning will flag risks of non-adherence before they happen. Wearables and remote monitoring will feed continuous data loops, enabling real-time interventions.

This isn’t science fiction. It’s the natural evolution of truly patient-centric care—hyper-personalized support, delivered at scale. Organizations that invest in this foundation now will lead in a value-based healthcare landscape where outcomes matter most.

The Shift from Support to True Care

Patient support is not a single touchpoint—it’s a journey. And it can’t be delivered with outdated, fragmented models. The future belongs to organizations that build PSPs that are seamless, scalable, compliant, and deeply human.

At Hexaware, we’re helping pharma and healthcare leaders make that shift—modernizing programs so patients don’t just get support, they feel supported. Let’s build the next generation of PSPs together. Talk to our team about how to make your PSP frictionless and future-ready.

About the Author

Varun Sethuraman

Varun Sethuraman

Senior Domain Consultant

Varun is a Senior Domain Consultant with Hexaware's Life Sciences & Healthcare Solutions team, bringing extensive expertise in R&D, consulting, and strategic management within the life sciences and healthcare sectors. At Hexaware, he leads the Commercial and Digital Consulting practice, delivering a comprehensive suite of services across the commercial lifecycle to drive growth and unlock value for global clients.

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FAQs

Hexaware’s approach to transforming Patient Support Programs (PSPs) starts with patient journey optimization, not just system upgrades. Unlike traditional models that focus on isolated processes, we take a holistic view of patient experience management—from patient onboarding automation to long-term digital health engagement.

Our PSP implementation framework combines deep expertise in healthcare and  pharma patient services with advanced automation, analytics, and compliance-by-design. This ensures organizations not only improve patient retention but also create scalable, flexible PSPs that adapt as therapies and markets evolve. The result is a frictionless experience for patients and measurable value for providers and pharma companies.

Patient Support Programs (PSPs) are structured initiatives, often offered by pharmaceutical manufacturers or specialty providers, designed to help patients start and stay on therapy. PSPs typically include services like patient onboarding automation, insurance verification, education, adherence reminders, and financial assistance.

Modern PSPs go beyond basic support to drive patient engagement and digital health engagement, ensuring a seamless experience across every touchpoint. When implemented effectively, they enable better patient experience management, reduce therapy abandonment, and directly improve patient retention.

Automation eliminates the friction points that frustrate patients and slow down care. By automating tasks like intake, consent, and insurance verification, organizations can simplify patient onboarding automation—getting patients on therapy faster and with less administrative hassle.

Automated reminders, personalized outreach, and integrated workflows enhance patient engagement and keep patients connected throughout their treatment. For care teams, automation frees up time to focus on empathetic, high-value interactions. Ultimately, automation drives smoother patient journey optimization and stronger digital health engagement, leading to higher satisfaction and improved patient retention.

When PSP implementation is modernized with the right mix of automation, integration, and analytics, it directly impacts outcomes. A streamlined PSP reduces delays in treatment starts through faster patient onboarding automation, provides continuous support to keep patients engaged, and enables proactive interventions when adherence risks are detected.

By aligning PSPs with patient journey optimization and embedding tools for real-time patient experience management, organizations not only improve patient retention but also see measurable gains in adherence, satisfaction, and overall therapeutic success. In short: better programs create better health outcomes.

The most effective technologies for automating Patient Support Programs are those that bring together integration, scalability, and intelligence:

  • CRM platforms like Salesforce Health Cloud for unified patient experience management
  • Automation tools for faster patient onboarding automation, insurance verification, and consent capture
  • Analytics and AI for real-time patient journey optimization and adherence risk detection
  • Digital health engagement tools (apps, portals, wearables) that keep patients connected outside the clinic

Together, these technologies enable PSPs to scale across therapies, drive pharma patient services excellence, and improve patient retention.

Sticking with outdated Patient Support Programs comes with serious risks. Manual processes and disconnected systems frustrate patients, leading to drop-offs during onboarding and reduced adherence. This weakens patient engagement, undermines digital health engagement, and drives down satisfaction.

For pharma companies, ineffective PSPs translate to wasted investment, poor outcomes data, and missed opportunities in pharma patient services. Most importantly, patients lose trust in the system. Without modern PSP implementation focused on patient journey optimization, organizations risk falling behind in both market competitiveness and patient outcomes.

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